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How Do We Get Sickle Cell

Sickle cell is passed down through our genes so as you can see from my picture above if both parents have a trait then it is likely your child will either  be born with a trait or sickle-cell and yes there is all so a 25% chance that the will have nothing but don’t hold me to that has I’m not 100% sure that is true . You can also get sickle cell if one parent has a trait and the other parent is a sickler e.g carrier.

Sickle Cell trait:

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Sickle cell trait (SCT) is not a disease, but having it means that a person has inherited the sickle cell gene from one of his or her parents. People with SCT usually do not have any of the symptoms of sickle cell disease (SCD) and live a normal life.

Please note that I said usually have no symptoms, I do know some people who has got a trait has experienced symptoms that a person with sickle cell would.

I was born premature and with a G6PD deficiency so my sickle cell got masked by this but with after much testing as they tried everything they could think of to treat the G6PD as my symptoms were the same they decided to test me for sickle cell and it was only then my sickle cell came to light

What is G6PD deficiency? 

G6PD deficiency is an inherited condition. It is when the body doesn’t have enough of an enzyme called G6PD (glucose-6-phosphate dehydrogenase). This enzyme helps red blood cells work properly. A lack of this enzyme can cause hemolytic anemia. This is when the red blood cells break down faster than they are made.

What causes G6PD deficiency?

G6PD deficiency is inherited. This means it is passed down from parents through their genes.

Women who carry one copy of the gene can pass G6PD deficiency to their children.

  • Men who get the gene have G6PD deficiency.

  • Women who get the gene are carriers. They often don’t have symptoms. But they can pass the gene onto their children.

The severity of the disorder varies, depending on the group. In African-Americans, the problem is mild. It mainly affects older red blood cells. In whites, the disorder is often more serious. In this group, young red blood cells are affected.

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